DRUGS
Drug entities are the central focus of PGxDB. Users can search for 6,259 drug-like molecules (small molecules and biologics) interacting with one or more proteins. Among these, 432 are biologics (including antibodies, vaccines, recombinant therapeutic proteins, or other biological molecules) and 5,827 are small molecules. Drugs are further classified into six categories based on their clinical development and approval status: approved, vet-approved, nutraceutical, experimental, investigational, and illicit. Most drugs have assigned ATC codes. We provide network views where drugs, their interacting proteins, and associated diseases are organized based on ATC codes. Other aspects are also presented, such as adverse drug reactions, pharmacogenomics, and statistics.
As an example, the image on the right shows the drug-protein interactions and drug-disease associations for Dexamethasone (DrugBank identifier = DB01234) with 16 assigned ATC codes:
R01AD53,
D07XB05,
R01AD03,
D10AA03,
S01CB01,
S02CA06,
S03CA01,
C05AA09,
S01CA01,
D07CB04,
H02AB02,
S01BA01,
A01AC02,
S03BA01,
D07AB19,
S02BA06
Search by Drugbank ID or drug name
Random drug examples
| Drugbank ID | Drug name | ATC code | Drug type | Clinical status | Adverse drug reactions | Reference |
|---|---|---|---|---|---|---|
| DB00001 | Lepirudin | B01AE02 | Biotech | Approved | NA | Go to Drugbank |
| DB00002 | Cetuximab | L01XC06 | Biotech | Approved | NA | Go to Drugbank |
| DB00004 | Denileukin diftitox | L01XX29 | Biotech | Approved | NA | Go to Drugbank |
| DB00005 | Etanercept | L04AB01 | Biotech | Approved | NA | Go to Drugbank |
| DB00006 | Bivalirudin | B01AE06 | Small Molecule | Approved | NA | Go to Drugbank |
| DB00007 | Leuprolide | L02AE51, L02AE02 | Small Molecule | Approved | NA | Go to Drugbank |
| DB00008 | Peginterferon alfa-2a | L03AB11, L03AB61 | Biotech | Approved | NA | Go to Drugbank |
| DB00009 | Alteplase | B01AD02, S01XA13 | Biotech | Approved | NA | Go to Drugbank |
| DB00010 | Sermorelin | V04CD03, H01AC04 | Biotech | Approved | NA | Go to Drugbank |
| DB00011 | Interferon alfa-n1 | L03AB06 | Biotech | Approved | NA | Go to Drugbank |
| DB00012 | Darbepoetin alfa | B03XA02 | Biotech | Approved | NA | Go to Drugbank |
| DB00013 | Urokinase | B01AD04 | Biotech | Approved | NA | Go to Drugbank |
| DB00014 | Goserelin | L02AE03 | Small Molecule | Approved | 41 (View Details) | Go to Drugbank |
| DB00015 | Reteplase | B01AD07 | Biotech | Approved | NA | Go to Drugbank |
| DB00016 | Erythropoietin | B03XA01 | Biotech | Approved | NA | Go to Drugbank |
| DB00017 | Salmon calcitonin | H05BA01 | Biotech | Approved | NA | Go to Drugbank |
| DB00018 | Interferon alfa-n3 | Not assigned | Biotech | Approved | NA | Go to Drugbank |
| DB00019 | Pegfilgrastim | L03AA13 | Biotech | Approved | NA | Go to Drugbank |
| DB00020 | Sargramostim | L03AA09 | Biotech | Approved | NA | Go to Drugbank |
| DB00022 | Peginterferon alfa-2b | L03AB10, L03AB60 | Biotech | Approved | NA | Go to Drugbank |